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Antioxidant Interventions in Hashimoto's: The Clinical Evidence While direct human clinical trials of oral glutathione supplementation specifically for Hashimoto's thyroiditis are still limited, the evidence from related antioxidant interventions is highly instructive: A comprehensive systematic review and meta-analysis published in Thyroid (2024) - conducted by researchers at the University of Bern, Switzerland - analyzed 35 randomized controlled trials (RCTs) involving 2,358+ participants with Hashimoto's thyroiditis

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This is achieved by the ability of erythrocytes to scavenge and detoxify exogenous neutrophils-, monocytes- or endothelial cells-derived reactive oxygen species (ROS) and reactive nitrogen species (RNS) [53, 54]