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However, research on this pentadecapeptide is primarily animal-based and in vitro , with no published full-text clinical studies despite some authors mentioning a phase 1 trial on BPC-157 as an anti-ulcerative agent in IBD patients [6]

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Conventional thinking posits that a primary defect in adaptive immunity promotes recruitment and entry of peripherally activated lymphocytes into the CNS across a disrupted bloodbrain barrier where a complex cascade of autoimmune/inflammatory processes culminates in edema, and destruction of myelin, axons and oligodendrocytes (for detailed reviews see Dendrou et al., 2015