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On the low end, a cigarette may contain about 6 mg of nicotine

Additional studies on large cEDS cohorts are expected to confirm the limited multisystemic involvement and rather favorable natural history of cEDS and to explore possible genotype-phenotype correlations, which would permit to establish management guidelines

However, there are some questions about the insurance provisions and a floor amendment may be in the works to address any issues, she added

A valuable potential next step would be the development of future scenario-specific ISRMs that account for expected changes in background air pollutant concentrations