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Golvatinib is another class II c-MET inhibitor used in clinical trials and are large hydrophobic molecules that binds to the back pocket of c-MET and are usually less specific [115]

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Nat Genet 37:353355 Hutchins JR, Toyoda Y, Hegemann B, Poser I, Heriche JK, Sykora MM, Augsburg M, Hudecz O, Buschhorn BA, Bulkescher J, Conrad C, Comartin D, Schleiffer A, Sarov M, Pozniakovsky A, Slabicki MM, Schloissnig S, Steinmacher I, Leuschner M, Ssykor A, Lawo S, Pelletier L, Stark H, Nasmyth K, Ellenberg J, Durbin R, Buchholz F, Mechtler K, Hyman AA, Peters JM (2010) Systematic analysis of human protein complexes identifies chromosome segregation proteins