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Without liver transplant, acute liver failure due to idiosyncratic drug injury carries a high mortality rate (up to 80%) If encephalopathy or coagulopathy develops in patients who have hepatocellular DILI and jaundice, they should be referred to a liver transplant center Pharmacogenetics There is considerable interest in identifying the genes that contribute to DILI

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In a recent survey of 2232 people with Hashimotos, 50% reported it was helpful, 64% reported a reduction in pain, 35% reported an increase in energy, and 12.5% showed improvement in thyroid antibodies