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the invention provides methods of treating dementia patients at various stages of dementia, and/or of slowing and/or preventing the progression of dementia to later stages of dementia, or even or reversing the "staging" from advanced to moderate or early, or from moderate to early, stage

EE is an intensive intervention ( Anti-apoptotic drugs High expression of the pro-apoptotic protein p53 in NSCs leads to disruption of endogenous neurogenesis after neonatal HIBD ( Anti-inflammatory drugs Neuroinflammation has been demonstrated to inhibit neurogenesis and the presence of various inflammatory components, such as immune cells, cytokines, or chemokines, plays a role in regulating the survival, proliferation, and maturation of NSCs ( via blocking microglia activation, which may also apply to neonatal HIBD, because neuroinflammation is also one of the important injuries mechanisms of neonatal HIBD ( Endogenous growth factor analogues Numerous growth factors can increase the proliferation of endogenous NSCs under a variety of conditions, thus promoting the endogenous neurogenesis process