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4.3 million hectares of land are used to grow tobacco (2012) 90% of tobacco farming is in low- to middle- income countries, with the top being China, Brazil, and India

10.1016/j.toxrep.2019.11.008 Toxicol

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G-CSF has also recently been suggested as an orchestrator of inflammation in COPD 61 , and has been found to be elevated in the bronchoalveolar lavage fluid of smokers 61