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doi: 10.3389/fimmu.2026.1737847 Received 02 November 2025 Revised 09 January 2026 Accepted 12 January 2026 Published 30 January 2026 Volume 17 - 2026 Edited by Ana Carolina Martinez-Torres, Autonomous University of Nuevo Len, Mexico Reviewed by Karla Alvarez-Valadez, INSERM U1138 Centre de Recherche des Cordeliers (CRC), France Helen Yarimet Lorenzo-Anota, University of Technology Compiegne, France Updates Copyright 2026 Guo, Wang, Zhang, Xie, Chen, Ma, Guo and Zhang

Sterile water becomes more relevant when a compound is intended to be used entirely in one sitting, or when a prescriber has specifically indicated that a preservative-free solution is required for example, due to sensitivity to benzyl alcohol