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It is observed by many that e-cigarette to be harmless than traditional cigarettes, still a lot of the devices contain nicotine and inhaling their vapors exposes users to toxic substances, including lead, cadmium, and nickel, heavy metals that linked with significant health problems (Grana, 2014).In developing countries due to lack of infrastructure, and funds are the major drawback towards the success of smoking control and smoking cessation, rich countries should extend help in the implementation of intervention programs

Heptachlor was substituted, then discontinued in the early 1960s in favor of another pesticide, mirex, which in turn was found to harm wildlife and marine life, and possibly to cause cancer in human beings

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