Mice deficient in -glutamyl transpeptidase have been generated, and these animals exhibit glutathionuria, glutathionemia, growth failure, cataracts, lethargy, shortened life span, and infertility (Lieberman et al., 1996
2011, pp
doi: 10.1093/nar/gkz850
These treatments include NAC, melatonin, coQ10, thiamine, riboflavin, niacin B3, vitamins B6 and B12, folate, vitamins A, C, D and K, calcium, phosphorus, magnesium, sodium, potassium, chloride, iron, zinc, copper, selenium, iodine, vitamin E, vitamin K, L-arginine, inositol, biotin, pantothenic acid, eicosatetraenoic acid (EPA), docosahexaenoic acid (DHA) and various combinations of the above (188)