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[57] Addition of 400,000 IU/week vitamin A to a conventional chemotherapy regimen (doxorubicin, bleomycin, 5-fluorouracil, and methotrexate) led to improved survival with less than the expected severity of side effects compared with historical controls

However, total tyrosyl phosphorylation (Figure S5A) and ERK phosphorylation (Figure S5B) were not altered in Tamoxifen resistant cell with Sorafenib treatment, suggesting that the effect of Sorafenib on cell growth is unlikely through inhibition of RTKs or RAF

Roman (STScI), J