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If you have one MTHFR C677T mutation, then your ability to detoxify the mercury is decreased by 50%

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The calcium concentration gradient between the inside of the cell [10 -7 M] and the extracellular fluid [10 -3 M] is maintained by an active membrane-associated calcium and magnesium effluxing adenosine triphosphatase [ATPase] enzyme system which is an important potential target for toxicants