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PMCID: PMC5849623 Marini JC, Forlino A, Cabral WA, Barnes AM, San Antonio JD, Milgrom S, Hyland JC, Krkk J, Prockop DJ, De Paepe A, Coucke P, Symoens S, Glorieux FH, Roughley PJ, Lund AM, Kuurila-Svahn K, Hartikka H, Cohn DH, Krakow D, Mottes M, Schwarze U, Chen D, Yang K, Kuslich C, Troendle J, Dalgleish R, Byers PH

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Dihydroberberine activates AMPK, a key cellular energy sensor that promotes fat burning, improves insulin sensitivity, and supports healthy glucose metabolism

The peptide is celebrated for its ability to promote collagen synthesis, directly addressing one of the key aesthetic concerns associated with hormonal shifts