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R 0 represents viral transmissibility, indicating an average number of new infections transmitted by an infected individual in a totally nave population

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In patients with refractory IBD, co-administration of anti-TNFs with vedolizumab, ustekinumab or natalizumab has shown promising results in case reports and case series and was not accompanied by a substantial increase in the incidence of serious adverse events, such as serious infections [203]

The MASLD epidemic, with its high prevalence in the general population, is attributed to numerous factors, the most important being the availability of high-calorie foods and reduced levels of physical activity