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In a different study, the impact of methotrexate was evaluated in a Swiss mouse skin tumor model methylcholanthrene (MCA)

However, the foundational mechanism paper (Benoist et al., 2014 in J Pharmacol Exp Ther) establishing Dihexas HGF/c-Met pathway activation was formally retracted in April 2025 after being flagged since 2021

Regul Pept 2013

Thus, the IL-17 agonist, a promising immunomodulator, represents a valuable candidate for the development of novel antifungal agents (Zhang et al., 2025)