Stuart KA, Riordan SM, Lidder S, Crostella L, Williams R, Skouteris GG
Melatonin-mediated BMI1 regulation and the latter's role in inducing mitophagy to curb oxidative stress could set a path for establishing melatonin as a therapeutic candidate for Parkinsons Disease
We and others also observed that Rickettsia species encode a conserved GSH S-transferase GstA 10 , which is a homolog of a cell division protein FzlA that adopts a GST fold but does not bind GSH in vitro 58,59
Strengthening this system through lifestyle, precursor supplementation, and, where appropriate, modern delivery methods may not cure diabetes, but it offers a way to slow its progression, protect vulnerable organs, and reshape metabolic health for the long run