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In the future, the regulatory field around peptides may partly mirror the regulation of dietary supplements: they are regulated, but their safety must be supported by evidence of no harm, and promises about outcomes must be realistic and tightly tied to available data

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Translational Considerations and Safety NNMT has emerged as a systems-level regulator linking methylation capacity, NAD biology, and adipocyte energetics

Clear manifestions of dysautonomia have been frequently reported for ME/CFS and long COVID, but much less so for long Lyme/PTLDS, for which further research on this topic would be welcome