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Interestingly, the SOD activity in the red blood cells was elevated in ASD children if compared to the control group and that is probably because this mechanism acts against the cell damage caused by the oxidative stress in the brain (Pangrazzi et al., 2020a)

By increasing selenoprotein synthesis and thereby suppressing CRP production, Se supplementation can compensate for lower levels of Se in serum and liver, and as a result, inflammation will be attenuated [50] Although Se supplementation with sodium selenite decreased CRP levels in acute respiratory distress syndrome (ARDS) patients during the study period, the differences between Se-supplemented and control groups were not significant [51]

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