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In the discovery paper, the anti-obesity efficacy of the molecule in mice exceeded that of a maximally effective dose of semaglutide, and mechanistic dissection attributed the additional effect specifically to increased energy expenditure combined with reduced food intake

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the Norleual and D-NIe-Tyr-IIe-NH-(CH 2 )5-CONH 2 samples were precipitated by adding 3 vol of ice-cold acetonitrile (ACN) and the samples were vortexed vigorously

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The role of tirzepatide, dual GIP and GLP-1 receptor agonist, in the management of type 2 diabetes: the SURPASS clinical trials

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Cagrilintidesemaglutide in adults with overweight or obesity and type 2 diabetes (REDEFINE 2)

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