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Upon addition of GSH, a new emission peak at 520 nm emerges and the intensity is rising along with the increase of GSH concentration (Figure 4A)

Molecular pathways: reactive oxygen species homeostasis in cancer cells and implications for cancer therapy

For instance, in the fibrotic microenvironment where lactate accumulates and is taken up by macrophages and myofibroblasts, p300 has been implicated in promoting lactylation at macrophage-related loci, potentially contributing to the progression of pulmonary fibrosis [81]