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It is used in the treatment and prevention of vitamin B12 deficiency in patients with conditions such as: Addisonian (pernicious) anemia Malabsorption Atrophic gastritis Prolonged treatment with metformin Small bowel bacterial overgrowth (SIBO) Total or partial gastrectomy Infection with the fish parasite Diphyllobothrium latum Helicobacter pylori infection Pancreatic dysfunction Pancreatic or bowel malignancy Dietary deficiency (e.g

wellness support of vitamin B shots Its common in wellness settings to hear B12 touted as an energy booster or metabolism aid

Any nausea tends to be mild and transient rather than a persistent feature of use

Phase 2b primary endpoints failed in the largest published trial