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FIGURE 2 3 Redox dysregulation in disease states 3.1 GSH in peripheral immune cell infiltration Several studies indicate that neuroinflammatory changes associated with neurodegeneration compromise the BBB or its function by disrupting transport systems, facilitating the infiltration of immune cells, and influencing the BBBs role as a signaling interface

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The plant glutathione peroxidase-like enzymes (GPXL) family consists of multiple isoenzymes with distinct subcellular locations, exhibiting different tissue-specific expression patterns and involvement in various types of stress

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