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Warnings Benzyl Alcohol Patients who have early Leber's disease (LHON) a hereditary disease that causes optic nerve atrophy have been found to suffer severe and swift optic atrophy when treated with vitamin B12

Particularly when its chronic, patients often wind up in kidney failure and on dialysis, which has basic scientists and physicians alike looking for better interventions

The folate-cobalamin interaction is pivotal for normal synthesis of purines and pyrimidines and the transfer of the methyl group to cobalamin is essential for the adequate supply of tetrahydrofolate, the substrate for metabolic steps that require folate

Subcutaneous injections are administered under the skin into fat between the skin and muscle