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29 Although the physical basis for the barrier and its physiologic function in the normal lens remain unclear, the location of the barrier at or near the nucleuscortex boundary strongly suggests that it plays a major role in the distinctive structural and functional properties of these two regions of the lens

Different kinds of membranes are used in filters and pore size of these membranes proves to be a physical barrier for microbes

Sulforaphane-mediated KEAP1 modification releases NRF2 from degradation and results in NRF2 phosphorylation and nuclear translocation (Figure 2)

However, these compounds have limitations in solubility and half-life, necessitating further optimization to enhance clinical applicability