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Individuals experiencing low energy levels, fatigue, or sluggishness despite adequate sleep and nutrition

In patients with reduced renal clearance, excessive magnesium intake may contribute to clinically significant hypermagnesemia, with manifestations ranging from mild gastrointestinal or neuromuscular symptoms to hypotension, bradycardia, respiratory depression, and cardiopulmonary arrest at higher serum magnesium levels, as summarized in Table 4

Subsequently, HaCaT keratinocytes viability after treatment with test compounds, GHK, CuCl 2 and Cu(OAc) 2 were assessed using MTT assay and LDH assay