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Klobucher KN, Badger R, Foxall T, Erickson PS

GHK-Cu upregulates genes involved in collagen synthesis, extracellular matrix assembly, and tissue remodeling while downregulating genes associated with tissue destruction (matrix metalloproteinases, inflammatory cytokines)

Oxidative stress is significant because this renders the central nervous system exquisitely sensitive to free radical attack

In summary, in general, we identified the claims data used in the development of the FY 2024 MS-LTC-DRG relative weights in this proposed rule by trimming claims data that would have been paid the site neutral payment rate had the provisions of the CARES Act not been in effect