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Next, Avliyakulov NK, et al

10.1016/j.immuni.2014.09.008 26 RossS.EikelboomJ.AnandS

With regard to distribution , for drugs such as diazepam 1 and penfluridol 5 that are substantially distributed into adipose tissue, greater adiposity is associated with greater storage of the drug in lipid reservoirs, and hence greater availability of the drug for return to blood as blood levels fall due to metabolism