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Description

Under low oxygen conditions, HIF-1 stabilizes and activates, regulating the expression of thousands of genes including glycolytic enzymes, Vascular Endothelial Growth Factor (VEGF), and Erythropoietin (EPO) (Figure 2

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The term does not describe a third GLP receptor

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However, the analysis revealed that the protective effect, while statistically significant for both sexes, was more pronounced in males than females, potentially due to hormonal modulation of Ang-II pathways

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