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507 The brains of individuals with preclinical AD (PCAD) and AD exhibit oxidative damage to a variety of molecules, e.g., accumulation of protein carbonyls (PCs) in regions that are rich in A-peptide-containing SPs, increased lipid peroxidation in AD and PCAD hippocampi and elevated DNA damage

doi: 10.1016/j.clinthera.2019.04.028 5

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If they didn't budge, consider whether the dose was sufficient, the duration was long enough, or whether BPC-157 was the right tool for your specific issue