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165 In another example, Wang et al 100 gave the cationic AMP Polybia-MPI to the multi-drug resistant leukemia cell line K562/ADM that was 201 times resistant to doxorubicin and 14.7 times resistant to actinomycin

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Intramuscular administration allows B12 to bypass hepatic metabolism and enter systemic circulation directly, which is why this route differs from oral supplementation