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Recent breakthroughs in nanotechnology have provided novel approaches for overcoming the BBB

Protection Against NSAID-Induced Damage Non-steroidal anti-inflammatory drugs (NSAIDs) provide relief from pain and inflammation, but they often come at a cost to the gastrointestinal tract [6]

ROS-mediated outer mitochondrial membrane permeabilization and cytochrome c (an apoptosis-inducing agent) translocation, to the cytosol begin the intrinsic mitochondrial apoptotic pathway, where they activate caspase-dependent cell apoptosis [42]