only extreme, high-dose cosmetic treatments are linked to pigment lightening
There is insufficient evidence to suggest that nucleoside analogs used in the treatment of HIV infection (i.e., zidovudine [AZT], didanosine [ddI], zalcitabine [ddC], and stavudine [d4T] or certain cancer chemotherapy agents (i.e., ifosfamide, cisplatin) increase the risk of secondary L-carnitine deficiency (135)
However, because of the small size of the current trial, the lack of randomization versus untreated short adolescents and the short-term surveillance, we cannot recommend this off label treatment, which should remain in a clinical research setting
Widely recognized for its role in cellular energy metabolism, L-Carnitine is essential for transporting long-chain fatty acids into the mitochondria, where they are oxidized to produce energy