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10.1016/j.biopha.2023.114930 23 JiaD.GaoP.LvY.HuangY.ReillyJ.SunK.et al (2022)

Those seeking improved mood and cognitive function: B12 can help enhance mood and mental clarity

Its imbalanced receptor affinity and biased signaling provide enhanced insulin secretion and improved metabolic outcomes beyond selective GLP-1 agonism

Most available evidence suggested that glomus (type I) cells are the initial sites of transduction and they release transmitters in response to hypoxia, which in turn depolarize the nearby afferent nerve ending, leading to an increase in sensory discharge