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The absence of human teratogenicity data means risk cannot be quantified, but early first-trimester exposure (gestational weeks 38) coincides with organogenesis when developmental signaling is most vulnerable to external modulators

Most patients with AF exhibit a recognized form of atrial cardiomyopathy (AtCM), which has been proposed to cause strokes independently of AF, although evidence supporting this is limited

This form is well absorbed and more stable throughout the digestive system

For each exercise, strength increased for both groups (P = 0.0001) through 14 weeks of training, with little improvement thereafter