Copper compounds are also used as actives or excipients in cosmetic and pharmaceutical products, e.g., copper peptide for skin regeneration purposes, cupric aspirinate and cupric salicylate for rheumatoid arthritis treatment, copper conjugated dendrimer for anti-tumoral activity, and copper liposome for enhanced stability of doxorubicin 5,6,7,8,9
Glutathione is in a class of molecules called anti-oxidants, whose primary job is to alleviate oxidative stress
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These parameters may be evaluated using tumor biopsy specimens and patient-derived samples through a combination of complementary experimental and clinical methodologies, including immunohistochemistry or spatial proteomics to assess FSP1 expression and localization, metabolomics or lipidomics-based omics approaches to quantify CoQ redox state and lipid peroxidation signatures and functional ferroptosis-sensitivity assays in patient-derived tumor models such as organoids or xenografts
