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Comparing serial concentrations of CSEs for inflammatory response, 3R4F and Spectrum cigarettes showed a dose-dependent increasing trend in TNF- release from THP-1 derived macrophages (Supplementary file Figure 5) until the 15% and 30% dilution, respectively (only moderate cytotoxicity was observed at this dilution in BEAS-2B cells)

Student-facing staff who include teachers, teaching assistants, principals, school nurses, school councillors, administrators or any other staff who connect with students will also be included in this research

Because they are produced in the curing process and transfer into smoke, rather than being formed by combustion, it is possible to reduce nitrosamines by changing curing and storage practices

Fashion and smoking