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The inflammasome is a multiprotein complex that mediates the activation of caspase-1
without affecting BMDM viability
Processed human BAFF can either remain as a trimer
This proapoptotic activity is mediated predominantly through the activation of caspase-9
Temozolomide HY-P70191 The inflammasome is a multiproteinTemozolomide (NSC 362856) is an oral active DNA alkylating agent that crosses the blood brain barrier. Temozolomide is also a proautophagic and proapoptotic agent. Temozolomide is effective against tumor cells that are characterized by low levels of O6 alkylguanine DNA alkyltransferase (OGAT) and a functional mismatch repair system. Temozolomide has antitumor and antiangiogenic effects.
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