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Similarly, stria vascularis explants or dissociated cells of the stria vascularis from neonatal or adult cochleae are established in culture and are used to evaluate the otoprotective effects of various compounds against strial damage from ototoxic agents

CRISPR-Cas9 is a construct consisting of a guide RNA (gRNA) that targets the genetic loci of interest and the Cas9 endonuclease enzyme, which functions as a pair of nucleotide scissors that cleave the DNA at the target siteeffectively generating a double-stranded DNA break for subsequent genome editing [51]

doi: 10.1007/s00213-014-3650-y 111 MahmoodD.KhanamR.PillaiK

DDX First, parasites and colorectal cancer must be ruled out