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By employing 3D hydrogels typically characterized by small, micron-sized pores, the Kamm and Swartz labs have shown that (patho)physiologically relevant flow velocities can trigger migration of MDA-MB-231 in the upstream (against the flow) and downstream (with the flow) direction [231, 232]

Specific effects documented in research include proliferation of hair follicle progenitor cells, extension of the anagen (growth) phase of the hair cycle, increased hair follicle size and density, formation of new dermal papilla structures, enhanced wound-induced hair neogenesis, and prevention of follicle miniaturization

10.1186/s12943-018-0796-y Mol

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