Glutathione is synthesized in the cytosol of each cell by the action of two enzymes in an elegantly regulated system that allows it to be maintained at different homeostatic levels in different tissue types, with the liver, given its detoxification role, having the highest amounts
Achour O, Elmtaoua S, Zellama D, Omezzine A, Moussa A, Rejeb J, Boumaiza I, Bouacida L, Rejeb NB, Achour A, Bouslama A (2016) The C677T MTHFR genotypes influence the efficacy of B9 and B12 vitamins supplementation to lowering plasma total homocysteine in hemodialysis
[5] More Effective at Raising Arginine Levels - Studies show that L-citrulline supplementation increases plasma L-arginine concentrations more effectively than an equivalent dose of L-arginine itself
doi: 10.1016/j.psc.2014.05.006 6 Swierkosz-LenartKDos SantosJFAEloweJClairAHBallyJFRiquierFet al