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Description

Based on the phase 2 and phase 3 trial protocols: Weeks 1-4: 1 mg once weekly Weeks 5-8: 2 mg once weekly Weeks 9-12: 4 mg once weekly Weeks 13-16: 8 mg once weekly Weeks 17 onward: 12 mg once weekly (maximum dose) The starting dose of retatrutide is deliberately low because the triple-agonist mechanism produces more intense initial side effects than single-pathway compounds

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doi: 10.1136/gutjnl-2013-304833 198 XiaoPCaiXZhangZGuoKKeYHuZet al

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doi: 10.4103/JOACC.JOACC_16_21

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Lets first start with B12, in and of itself

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