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One ingredient that keeps showing up in longevity-focused skincare conversations is GHK-Cu, a copper peptide linked to skin regeneration, collagen support, and overall skin health

As for the two methods by which GHK-Cu may be administered: GHK-Cu cream side effects Researchers have not attributed any side effects to topical GHK-Cu formulas tested to date, and all available research shows that the peptide is non-toxic and a non-irritant when applied directly to the skin [5]

Safety was assessed by questioning the patient weekly during ARA 290 administration and throughout the 12-wk follow-up for the occurrence of adverse events