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With the easily designed structure and appropriate molecular size between small molecules and large proteins, peptide therapeutics displayed a high binding affinity with the PPI interface and good cell penetrability, which seem to be promising candidates that combine the advantages of the above two therapeutic arsenals (Table 1) [1520]

What is more, p53 activation in renal tubular epithelial cells was closely related to the deterioration of AKI (Zhang et al., 2014)

Tunal-Akbay T, Sehirli O, Ercan F, et al

While patients may occasionally notice swollen lymph nodes during treatment, current clinical trial data and FDA prescribing information do not establish tirzepatide as a recognized cause of lymphadenopathy