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It hit the science list, not the advice list, Asprey says

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Crouthamel C

Small molecules and nanoparticles that are water-soluble are able to permeate the blood-brain barrier (BBB) by the process of paracellular passive diffusion, which involves sliding down an inverse concentration gradient across tight junctions

503A compounded peptides are produced by licensed pharmaceutical facilities to individual prescriptions, with purity testing, sterility protocols, and regulatory oversight