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Figure 5 SLC7A11 and cell death In the initial investigations into cell growth conditions, researchers observed that a lack of SLC7A11-mediated cystine transport proved fatal for certain cells ( Figure 6 )

Adverse events were similar to those with GLP-1 and GIP-GLP-1 agonists

Whether this pathway plays an important role under pathological conditions is unknown, as CD163 has not been shown to uptake the dimer form of Hb, which is more relevant in SCD (Sulahian et al., 2000