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The purpose of the sub-classifications of Specified or Non-Specified on the Prohibited List is to recognize that it is possible for a substance to enter an athletes body inadvertently, and therefore allow a tribunal more flexibility when making a sanctioning decision

The authors identified TB4 as a potent wound healing factor with multiple complementary activities across the tissue repair cascade

Achieved IgG reduction is similar to that achieved by nipocalimab in human FcRn transgenic mice [360], and a concomitant therapeutic effect has been observed in animal models of arthritis, ITP and glomerulonephritis [414,415,416] and in clinical trials assessing safety (NCT01802697), increasing transplant success by negating pre-existing immunity (NCT02224820, NCT02426684, and NCT02475551), and in thrombotic thrombocytopenic purpura (NCT02854059)