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In sum, the and evidences presented here show that dopaminergic neurons are more sensitive to rotenone toxicity than non-dopaminergic neurons, amacrine cells of retina and astrocytes [55, 75-77], possibly due to their lesser effective oxidative mechanisms and reduced supply of antioxidants [30,78]

B., Azam, F., Sheikh, N

Predominantly found in organs like the liver, kidneys, and blood, Mo deficiency, particularly in molybdenum cofactor (MoCo) synthesis pathways, can lead to severe conditions such as MoCo deficiency (MoCD), impacting the proper functioning of MoCo-dependent enzymes like xanthine oxidase (XO), sulfite oxidase (SOX), aldehyde oxidase (AO), and mitochondrial amidoxime-reducing component (mARC)

The LPS model is simpler, but different bacterial sources of LPS as well as the dosage of LPS and the way of administering LPS may affect the success of modeling and the severity of AKI