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Amphetamine increases the concentration of dopamine in the synaptic cleft by entering the presynaptic neuron by diffusing across the neuronal membrane directly or through DAT, competitive reuptake inhibition at the transporter, and finally, the reversal of dopamine transport through DAT (i.e., dopamine efflux) [159,160,161]

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The responses to S2 were stronger than when full-length spike was used as the antigen

This binding initiates an intracellular signaling cascade, promoting gene expression related to cell survival, proliferation, and migration, ultimately leading to the formation of new capillary networks and enhanced tissue perfusion