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Populations who should not use BPC-157: Pregnant or breastfeeding individuals (no safety data), anyone with a history of cancer (theoretical concern given pro-angiogenic mechanisms), individuals taking anticoagulants (some animal data suggest effects on platelet aggregation pathways), and anyone without access to sterile technique for injection preparation
Patients with reasonable life expectancy who have dysplastic BE (confirmed by an expert gastrointestinal pathologist) should undergo endoscopic resection (with EMR or ESD) of all visible lesions and subsequent endoscopic ablation of residual flat BE mucosa Goal of endoscopic eradication therapycomplete eradication of all intestinal metaplasia Risk Stratification of BE The histologic finding of dysplasia (LGD or HGD) is the best clinical tool for identifying patients at risk for progression to EAC
Published Research Lipolytic Activity Heffernan et al
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