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SMI, which is composed primarily of P

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Treated APP/PS1 mice showed significant improvements in spatial learning and memory compared to untreated transgenic controls, with molecular analysis confirming activation of PI3K/AKT signaling in hippocampal tissue

We also observed that although the total daily PUFA dosage that exhibited beneficial effects was in the range of 0.7 2 g EPA and 0.4 0.8 g DHA daily, with an administration period of three weeks to four months, positive vitamin D-based supplementation effects were observed after administering doses of 2000 IU/day or 50,000 IU/week between 8 weeks and 24 months